Stress and the Immune System: Dr Robert Ader

Thirty five years ago, Robert Ader, PhD serendipitously discovered a key part of our physiology that was not thought to exist.  The story begins with rats drinking water sweetened with saccharine.  Half the rats were simultaneously given low doses of Cytoxan to cause stomach pain.  (Cytoxan is a chemotherapy drug for cancer.)  It was no surprise that soon the rats associated the sweetened water with the pain and refused to drink it.

The experiment, conducted at the University of Rochester in New York State, then continued without the Cytoxan and Dr Ader gave these rats the water using an eye-dropper.  The rats who had never received Cytoxan continued to drink the sweetened water normally.  Unexpectedly, the rats previously treated with Cytoxan began to die from infections at a rate significantly higher than the rats who had never received it.  Considerable investigation was needed to reveal the cause.

Cytoxan, in addition to causing stomach discomfort, suppresses the immune system.  Dr Ader’s work revealed that, after the cytoxan injections, the saccharine water alone suppressed the immune system.  More experiments confirmed that tasting the saccharine triggered the nervous system to suppress the immune system.  Prior to this work, no such neuro-immune connection was thought to exist.  The process was analogous to the placebo effect where taking a sugar tablet you expect to relieve pain triggers changes in the brain that do relieve pain.

This work became the foundation of the field of psychoneuroimmunology which is beginning to unravel the connections between stress, the nervous system, the immune system and diseased organs.  In a cautionary tale for those of us who treat patients with psychophysiologic disorders (PPD), Dr Ader had to defend his work against people who drew unwarranted, unscientific conclusions from his findings.

Sadly, Dr Ader died recently, a few months short of his 80th birthday.  There is more information about his life and career in the New York Times obituary.

Tags: ,

2,273 Responses to “Stress and the Immune System: Dr Robert Ader”

  1. For the reason that the admin of this website
    is working, no doubt very shortly it will be renowned,
    due to its feature contents.

  2. It’s a pity you don’t have a donate button! I’d certainly donate to this outstanding blog!

    I guess for now i’ll settle for bookmarking and adding your RSS feed
    to my Google account. I look forward to new updates and will share this website with my Facebook group.
    Talk soon!

  3. Hurrah! In the end I got a website from where I be able to genuinely take helpful data concerning my study and knowledge.

  4. Such competition naturally give birth sales performance consulting to more prospective buyers
    and sellers together. Anyways, with additional purchasing power
    of teleseminars. Knowing the plans from the position within the page you just
    have to learn how to sell your car. Price, widely credited as the lesser known brands will sell your crafts directly
    to some good old memories.

    Feel free to visit my web site – sales Transformation consulting

  5. Article Source: the best ways to deal with stress by reading this books Bossypants audiobook and also a new earth
    audiobook. During the 1 hour or so it takes me
    to commute to and from work, I listen to an audio book. If you want to have more than one book on your MP3 player then storage capacity is something to consider.

    Also visit my blog; audiobook download

  6. This is very interesting, You are a very skilled blogger.
    I have joined your rss feed and look forward to seeking more of your magnificent post.
    Also, I have shared your web site in my social networks!

  7. Any person that desires to comprehend the specific strategy to eliminate unwanted
    bodyweight, it really is necessary to determine
    a specific type of fat loss diet that will offer the proper device for that you attain your weight loss plan.
    In fact even if they’re slightly heavier, they seldom appear bulky
    and oversized. Even if by some miracle you could turn off your feelings on your exgirlfriend, you’ll still couldn’t be friends along with
    her.

    Look into my homepage: Beauty And Nature

  8. An impressive share! I have just forwarded this onto a colleague who had been doing a
    little homework on this. And he in fact bought me
    dinner because I discovered it for him… lol. So allow me to reword this….
    Thanks for the meal!! But yeah, thanks for spending time to discuss this matter here on your website.

  9. It should be a virtue to both the cheap taxi orlando customer
    and the operator from potential physical threats. A treaty,
    legal contract or purchase order that took five weeks
    to reach Genoa from Madrid, could now be delivered in seven to 10 days.

    Also visit my page … https://twitter.com/TaxiOrlando1

  10. Link exchange is nothing else except it is simply placing
    the other person’s weblog link on your page at appropriate place and other person will also do same in support of you.

  11. Augusta says:

    96k545

    Alsso visit mmy webb pqge :: weeb ρage (Augusta)

  12. This is because scammers have been capitalizing on the concept that taints the good name of this business venture.
    The idea is that HCG helps your system lose excess fat–in areas like your upper thighs, your abdomen,
    your derriere, and underneath your arms–when you take in very
    small quantities of the hormone on a regular basis. When aiming to
    achieve a wear part, use sand paper as well as rub the corners
    and edges with the cabinets.

    Check out my website … weight loss hcg nz

  13. Wonderful article! That is the type of info that should be
    shared across the net. Disgrace on the search
    engines for no longer positioning this post upper!

    Come on over and seek advice from my site . Thanks =)

  14. This is very interesting, You are an overly skilled blogger.
    I have joined your feed and look forward to looking for more of your fantastic post.
    Additionally, I have shared your web site in my social networks

    There’s a lot of information to be found concerning honest rice cooker review, but rarely do you happen upon accurate and valuable websites on the issue.

  15. Strona świadczy o dobrych wydarzeniach, namawiam do dyskusji

    Also visit my page kserokopiarki

  16. Nice replies in return of this question with solid arguments and describing all about that.

    Also visit my site: magie voyance

  17. It’s going to be ending of mine day, however before end I am reading this fantastic piece of writing to improve my know-how.

    my web blog … sports photography charlotte nc

  18. help search says:

    Howdy! Do you use Twitter? I’d like to follow you if that would be ok.

    I’m undoubtedly enjoying your blog and look forward to new
    updates.

    Look at my website … help search

  19. When I originally commented I clicked the “Notify me when new comments are added” checkbox and now each time a comment is added I get four e-mails with the same comment.
    Is there any way you can remove people from that service?
    Cheers!

    Also visit my website; Business coach in melbourne, 69.173.64.102,

  20. VPS hosting says:

    The current job market accentuates the need for effective talent management,
    making Taleo an essential Saa – S provider. VPS hosting is one of the most innovating technologies that are available today.

    When you sign up for a VPS, you often pay for the resources
    that you use and only those resources.

  21. Hello, I want to subscribe for this webpage to get newest updates, therefore where can i do it please assist.

  22. Excellent post. I was checking continuously this blog
    and I am impressed! Very useful information specially
    the last part :) I care for such info much. I was looking
    for this particular info for a long time. Thank you and
    best of luck.

  23. Ƭhanks for sharing үouг thoսghts about mp3 zing vn news.
    Ɍegards

    Also vissit my web blog :: mp4 to mp3 file converter

Leave a Comment